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Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer

Epigenetic modifications are known to play critical roles in the expression of genes related to differentiation and dedifferentiation. Histone lysine demethylase KDM5B (PLU-1) catalyzes the demethylation of histone H3 on Lys 4 (H3K4), which results in the repression of gene expression. KDM5B is invo...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Yeh, I-Ju, Esakov, Emily, Lathia, Justin D., Miyagi, Masaru, Reizes, Ofer, Montano, Monica M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881367/
https://ncbi.nlm.nih.gov/pubmed/31776402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54184-0
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