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Phosphorylation of the histone demethylase KDM5B and regulation of the phenotype of triple negative breast cancer
Epigenetic modifications are known to play critical roles in the expression of genes related to differentiation and dedifferentiation. Histone lysine demethylase KDM5B (PLU-1) catalyzes the demethylation of histone H3 on Lys 4 (H3K4), which results in the repression of gene expression. KDM5B is invo...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881367/ https://ncbi.nlm.nih.gov/pubmed/31776402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-54184-0 |
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