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An in silico analysis of robust but fragile gene regulation links enhancer length to robustness

Organisms must ensure that expression of genes is directed to the appropriate tissues at the correct times, while simultaneously ensuring that these gene regulatory systems are robust to perturbation. This idea is captured by a mathematical concept called r-robustness, which says that a system is ro...

詳細記述

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書誌詳細
出版年:PLoS Comput Biol
主要な著者: Barr, Kenneth, Reinitz, John, Radulescu, Ovidiu
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881076/
https://ncbi.nlm.nih.gov/pubmed/31730659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007497
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