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An in silico analysis of robust but fragile gene regulation links enhancer length to robustness
Organisms must ensure that expression of genes is directed to the appropriate tissues at the correct times, while simultaneously ensuring that these gene regulatory systems are robust to perturbation. This idea is captured by a mathematical concept called r-robustness, which says that a system is ro...
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| 出版年: | PLoS Comput Biol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6881076/ https://ncbi.nlm.nih.gov/pubmed/31730659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007497 |
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