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An in silico analysis of robust but fragile gene regulation links enhancer length to robustness

Organisms must ensure that expression of genes is directed to the appropriate tissues at the correct times, while simultaneously ensuring that these gene regulatory systems are robust to perturbation. This idea is captured by a mathematical concept called r-robustness, which says that a system is ro...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS Comput Biol
Κύριοι συγγραφείς: Barr, Kenneth, Reinitz, John, Radulescu, Ovidiu
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6881076/
https://ncbi.nlm.nih.gov/pubmed/31730659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007497
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