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A sequence level model of an intact locus predicts the location and function of nonadditive enhancers

Metazoan gene expression is controlled through the action of long stretches of noncoding DNA that contain enhancers—shorter sequences responsible for controlling a single aspect of a gene’s expression pattern. Models built on thermodynamics have shown how enhancers interpret protein concentration in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Barr, Kenneth A., Reinitz, John
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513433/
https://ncbi.nlm.nih.gov/pubmed/28715438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180861
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