Germ-line genetic variation in the immunoglobulin heavy chain creates stroke susceptibility in the spontaneously hypertensive rat

The risk of cerebrovascular disease in stroke-prone spontaneously hypertensive rats (SHR-A3/SHRSP) arises from naturally occurring genetic variation. In the present study we show the involvement of SHR genetic variation that affects antibody formation and function in the pathogenesis of stroke. We h...

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Dhande, Isha S., Kneedler, Sterling C., Joshi, Aniket S., Zhu, Yaming, Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879812/
https://ncbi.nlm.nih.gov/pubmed/31608789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00054.2019
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