Germ-line genetic variation in the immunoglobulin heavy chain creates stroke susceptibility in the spontaneously hypertensive rat

The risk of cerebrovascular disease in stroke-prone spontaneously hypertensive rats (SHR-A3/SHRSP) arises from naturally occurring genetic variation. In the present study we show the involvement of SHR genetic variation that affects antibody formation and function in the pathogenesis of stroke. We h...

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Vydáno v:Physiol Genomics
Hlavní autoři: Dhande, Isha S., Kneedler, Sterling C., Joshi, Aniket S., Zhu, Yaming, Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2019
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879812/
https://ncbi.nlm.nih.gov/pubmed/31608789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00054.2019
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