Germ-line genetic variation in the immunoglobulin heavy chain creates stroke susceptibility in the spontaneously hypertensive rat

The risk of cerebrovascular disease in stroke-prone spontaneously hypertensive rats (SHR-A3/SHRSP) arises from naturally occurring genetic variation. In the present study we show the involvement of SHR genetic variation that affects antibody formation and function in the pathogenesis of stroke. We h...

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Udgivet i:Physiol Genomics
Main Authors: Dhande, Isha S., Kneedler, Sterling C., Joshi, Aniket S., Zhu, Yaming, Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879812/
https://ncbi.nlm.nih.gov/pubmed/31608789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00054.2019
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