Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension

BACKGROUND: Spontaneously hypertensive rats of the stroke‐prone line (SHR‐A3) develop hypertensive renal disease as a result of naturally occurring genetic variation. Our prior work identified a single‐nucleotide polymorphism unique to SHR‐A3 that results in truncation of the carboxy terminus of STI...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Heart Assoc
Egile Nagusiak: Dhande, Isha S., Zhu, Yaming, Kneedler, Sterling C., Joshi, Aniket S., Hicks, M. John, Wenderfer, Scott E., Braun, Michael C., Doris, Peter A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7335582/
https://ncbi.nlm.nih.gov/pubmed/32075490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.119.014142
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