Neuronal Vulnerability in Parkinson Disease and Putative Therapeutics: Should the focus be on axonal and synaptic terminals?

While current effective therapies are available for the symptomatic control of Parkinsońs disease (PD), treatments to halt the progressive neurodegeneration still do not exist. Loss of dopamine neurons in the substantia nigra pars compacta and dopamine terminals in the striatum drive the motor featu...

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Vydáno v:Mov Disord
Hlavní autoři: Wong, Yvette, Luk, Kelvin, Purtell, Kerry, Nanni, Samuel Burke, Stoessl, A. Jon, Trudeau, Louis-Eric, Yue, Zhenyu, Krainc, Dimitri, Oertel, Wolfgang, Obeso, Jose A., Volpicelli-Daley, Laura
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879792/
https://ncbi.nlm.nih.gov/pubmed/31483900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.27823
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