USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5

The Krüppel-like factor 5 (KLF5) transcription factor is highly expressed in basal type breast cancer and promotes breast cancer cell proliferation, survival, migration, and tumorigenesis. KLF5 protein stability is regulated by ubiquitination. In this study, ubiquitin-specific protease 3 (USP3) was...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Wu, Yingying, Qin, Junying, Li, Fubing, Yang, Chuanyu, Li, Zhen, Zhou, Zhongmei, Zhang, Hailin, Li, Yunxi, Wang, Xinye, Liu, Rong, Tao, Qian, Chen, Wenlin, Chen, Ceshi
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2019
Sujets:
Cell Biology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879341/
https://ncbi.nlm.nih.gov/pubmed/31624151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009102
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