USP3 promotes breast cancer cell proliferation by deubiquitinating KLF5

The Krüppel-like factor 5 (KLF5) transcription factor is highly expressed in basal type breast cancer and promotes breast cancer cell proliferation, survival, migration, and tumorigenesis. KLF5 protein stability is regulated by ubiquitination. In this study, ubiquitin-specific protease 3 (USP3) was...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Wu, Yingying, Qin, Junying, Li, Fubing, Yang, Chuanyu, Li, Zhen, Zhou, Zhongmei, Zhang, Hailin, Li, Yunxi, Wang, Xinye, Liu, Rong, Tao, Qian, Chen, Wenlin, Chen, Ceshi
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879341/
https://ncbi.nlm.nih.gov/pubmed/31624151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009102
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