Interplay of Amino Acid Residues at Positions 28 and 31 in NS5A Defines Resistance Pathways in Hepatitis C Virus Genotype 2

Hepatitis C virus (HCV) genotype 2 (GT2) represents approximately 9% of all viral infections globally. While treatment outcomes for GT2-infected patients have improved substantially with direct-acting antiviral agents (DAAs) compared to alpha interferon, the presence of polymorphisms in NS5A can imp...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Asante-Appiah, Ernest, Ingravallo, Paul, McMonagle, Patricia, Bystol, Karin, Xia, Ellen, Curry, Stephanie, Qiu, Ping, Black, Stuart, Chase, Robert, Liu, Rong, Lahser, Fred
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879245/
https://ncbi.nlm.nih.gov/pubmed/31527040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01269-19
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