Using State Transition Models To Explore How the Prevalence of Subtherapeutic Posaconazole Exposures Impacts the Clinical Utility of Therapeutic Drug Monitoring for Posaconazole Tablets and Oral Suspension

Therapeutic drug monitoring (TDM) has been recommended in guidelines for patients receiving posaconazole oral suspension, but its utility in patients receiving posaconazole tablet, which has an improved bioavailability, remains unclear. We used state transition models with first-order Monte Carlo mi...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Lewis, Russell E., Kontoyiannis, Dimitrios P., Viale, Pierluigi, Sarpong, Eric M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2019
Schlagworte:
Clinical Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879215/
https://ncbi.nlm.nih.gov/pubmed/31527039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01435-19
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