Using State Transition Models To Explore How the Prevalence of Subtherapeutic Posaconazole Exposures Impacts the Clinical Utility of Therapeutic Drug Monitoring for Posaconazole Tablets and Oral Suspension

Therapeutic drug monitoring (TDM) has been recommended in guidelines for patients receiving posaconazole oral suspension, but its utility in patients receiving posaconazole tablet, which has an improved bioavailability, remains unclear. We used state transition models with first-order Monte Carlo mi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Lewis, Russell E., Kontoyiannis, Dimitrios P., Viale, Pierluigi, Sarpong, Eric M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2019
Teme:
Clinical Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879215/
https://ncbi.nlm.nih.gov/pubmed/31527039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01435-19
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