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Treatment by Posaconazole Tablets, Compared to Posaconazole Suspension, Does Not Reduce Variability of Posaconazole Trough Concentrations

The delayed-release tablet formulation of posaconazole (POS-tab) results in higher plasma POS trough concentrations (C(min)) than the oral suspension (POS-susp), which raises the question of the utility of therapeutic drug monitoring (TDM). We aimed to compare the variability of the POS C(min) for t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Gautier-Veyret, Elodie, Bolcato, Léa, Roustit, Matthieu, Weiss, Stéphanie, Tonini, Julia, Brenier-Pinchart, Marie-Pierre, Cornet, Muriel, Thiebaut-Bertrand, Anne, Stanke-Labesque, Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6761514/
https://ncbi.nlm.nih.gov/pubmed/31358587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00484-19
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