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Assessment of human diploid genome assembly with 10x Linked-Reads data

BACKGROUND: Producing cost-effective haplotype-resolved personal genomes remains challenging. 10x Linked-Read sequencing, with its high base quality and long-range information, has been demonstrated to facilitate de novo assembly of human genomes and variant detection. In this study, we investigate...

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Publicat a:Gigascience
Autors principals: Zhang, Lu, Zhou, Xin, Weng, Ziming, Sidow, Arend
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6879002/
https://ncbi.nlm.nih.gov/pubmed/31769805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gigascience/giz141
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