ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab

Bevacizumab is included in an increasing number of clinical trials. To find biomarkers to predict and monitor treatment response, cancer and angiogenesis relevant mutations in tumour and circulating tumour DNA (ctDNA) were investigated in 26 metastatic melanoma patients treated with bevacizumab. Pat...

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Udgivet i:Sci Rep
Main Authors: Forthun, Rakel Brendsdal, Hovland, Randi, Schuster, Cornelia, Puntervoll, Hanne, Brodal, Hans Petter, Namløs, Heidi Maria, Aasheim, Lars Birger, Meza-Zepeda, Leonardo A., Gjertsen, Bjørn Tore, Knappskog, Stian, Straume, Oddbjørn
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877652/
https://ncbi.nlm.nih.gov/pubmed/31767937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53917-5
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