ctDNA detected by ddPCR reveals changes in tumour load in metastatic malignant melanoma treated with bevacizumab

Bevacizumab is included in an increasing number of clinical trials. To find biomarkers to predict and monitor treatment response, cancer and angiogenesis relevant mutations in tumour and circulating tumour DNA (ctDNA) were investigated in 26 metastatic melanoma patients treated with bevacizumab. Pat...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Forthun, Rakel Brendsdal, Hovland, Randi, Schuster, Cornelia, Puntervoll, Hanne, Brodal, Hans Petter, Namløs, Heidi Maria, Aasheim, Lars Birger, Meza-Zepeda, Leonardo A., Gjertsen, Bjørn Tore, Knappskog, Stian, Straume, Oddbjørn
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877652/
https://ncbi.nlm.nih.gov/pubmed/31767937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53917-5
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