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Cross-Species Functional Genomic Analysis Identifies Resistance Genes of the Histone Deacetylase Inhibitor Valproic Acid

The mechanisms of successful epigenetic reprogramming in cancer are not well characterized as they involve coordinated removal of repressive marks and deposition of activating marks by a large number of histone and DNA modification enzymes. Here, we have used a cross-species functional genomic appro...

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Auteurs principaux: Forthun, Rakel Brendsdal, SenGupta, Tanima, Skjeldam, Hanne Kim, Lindvall, Jessica Margareta, McCormack, Emmet, Gjertsen, Bjørn Tore, Nilsen, Hilde
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498369/
https://ncbi.nlm.nih.gov/pubmed/23155442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048992
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