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Heritability of skewed X-inactivation in female twins is tissue-specific and associated with age
Female somatic X-chromosome inactivation (XCI) balances the X-linked transcriptional dosages between the sexes. Skewed XCI toward one parental X has been observed in several complex human traits, but the extent to which genetics and environment influence skewed XCI is largely unexplored. To address...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6877649/ https://ncbi.nlm.nih.gov/pubmed/31767861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13340-w |
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