Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity

Manganese (Mn), an essential metal and nutrient, is toxic in excess. Toxicity classically results from inhalational exposures in individuals who work in industrial settings. The first known disease of inherited Mn excess, identified in 2012, is caused by mutations in the metal exporter SLC30A10 and...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Mercadante, Courtney J., Prajapati, Milankumar, Conboy, Heather L., Dash, Miriam E., Herrera, Carolina, Pettiglio, Michael A., Cintron-Rivera, Layra, Salesky, Madeleine A., Rao, Deepa B., Bartnikas, Thomas B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877324/
https://ncbi.nlm.nih.gov/pubmed/31527311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129710
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