Manganese transporter Slc30a10 controls physiological manganese excretion and toxicity

Manganese (Mn), an essential metal and nutrient, is toxic in excess. Toxicity classically results from inhalational exposures in individuals who work in industrial settings. The first known disease of inherited Mn excess, identified in 2012, is caused by mutations in the metal exporter SLC30A10 and...

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Udgivet i:J Clin Invest
Main Authors: Mercadante, Courtney J., Prajapati, Milankumar, Conboy, Heather L., Dash, Miriam E., Herrera, Carolina, Pettiglio, Michael A., Cintron-Rivera, Layra, Salesky, Madeleine A., Rao, Deepa B., Bartnikas, Thomas B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877324/
https://ncbi.nlm.nih.gov/pubmed/31527311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129710
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