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Paroxysmal nocturnal hemoglobinuria without GPI-anchor deficiency

Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by hemolysis, thrombosis, and bone marrow failure caused by defective expression of glycosylphosphatidylinositol-anchored (GPI-anchored) complement inhibitors. Most commonly, PNH is caused by loss of function of PIGA, wh...

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Detaylı Bibliyografya
Yayımlandı:J Clin Invest
Yazar: Brodsky, Robert A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877310/
https://ncbi.nlm.nih.gov/pubmed/31638602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131647
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