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Paroxysmal nocturnal hemoglobinuria without GPI-anchor deficiency
Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired disorder characterized by hemolysis, thrombosis, and bone marrow failure caused by defective expression of glycosylphosphatidylinositol-anchored (GPI-anchored) complement inhibitors. Most commonly, PNH is caused by loss of function of PIGA, wh...
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| Veröffentlicht in: | J Clin Invest |
|---|---|
| 1. Verfasser: | |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Clinical Investigation
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6877310/ https://ncbi.nlm.nih.gov/pubmed/31638602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI131647 |
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