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Paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare bone marrow failure disorder that manifests with hemolytic anemia, thrombosis, and peripheral blood cytopenias. The absence of two glycosylphosphatidylinositol (GPI)-anchored proteins, CD55 and CD59, leads to uncontrolled complement activation that...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215311/ https://ncbi.nlm.nih.gov/pubmed/25237200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-02-522128 |
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