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Advances in the Diagnosis and Therapy of Paroxysmal Nocturnal Hemoglobinuria
PNH is an uncommon acquired hemolytic anemia that often manifests with hemoglobinuria, abdominal pain, smooth muscle dystonias, fatigue, and thrombosis. The disease results from the expansion of hematopoietic stem cells harboring a mutation in a gene, PIG-A, that is required for the biosynthesis of...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2290854/ https://ncbi.nlm.nih.gov/pubmed/18063459 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.blre.2007.10.002 |
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