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Predictors of hemoglobin response to eculizumab therapy in paroxysmal nocturnal hemoglobinuria

BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal, hematopoietic stem cell disorder that manifests with hemolytic anemia and bone marrow failure. Eculizumab has been shown to improve anemia, decrease intravascular hemolysis, and reduce the risk of thrombosis. DESIGN AND METHODS: This...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: DeZern, Amy E., Dorr, Donna, Brodsky, Robert A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3673783/
https://ncbi.nlm.nih.gov/pubmed/23046169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejh.12021
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