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Predictors of hemoglobin response to eculizumab therapy in paroxysmal nocturnal hemoglobinuria
BACKGROUND: Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal, hematopoietic stem cell disorder that manifests with hemolytic anemia and bone marrow failure. Eculizumab has been shown to improve anemia, decrease intravascular hemolysis, and reduce the risk of thrombosis. DESIGN AND METHODS: This...
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| Hoofdauteurs: | , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2012
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3673783/ https://ncbi.nlm.nih.gov/pubmed/23046169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejh.12021 |
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