Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling

The parathyroid hormone 1 receptor (PTH1R) mediates the biologic actions of parathyroid hormone (PTH) and parathyroid hormone–related protein (PTHrP). Here, we showed that salt-inducible kinases (SIKs) are key kinases that control the skeletal actions downstream of PTH1R and that this GPCR, when act...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Nishimori, Shigeki, O’Meara, Maureen J., Castro, Christian D., Noda, Hiroshi, Cetinbas, Murat, da Silva Martins, Janaina, Ayturk, Ugur, Brooks, Daniel J., Bruce, Michael, Nagata, Mizuki, Ono, Wanida, Janton, Christopher J., Bouxsein, Mary L., Foretz, Marc, Berdeaux, Rebecca, Sadreyev, Ruslan I., Gardella, Thomas J., Jüppner, Harald, Kronenberg, Henry M., Wein, Marc N.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2019
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877304/
https://ncbi.nlm.nih.gov/pubmed/31430259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130126
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