Salt-inducible kinases dictate parathyroid hormone 1 receptor action in bone development and remodeling

The parathyroid hormone 1 receptor (PTH1R) mediates the biologic actions of parathyroid hormone (PTH) and parathyroid hormone–related protein (PTHrP). Here, we showed that salt-inducible kinases (SIKs) are key kinases that control the skeletal actions downstream of PTH1R and that this GPCR, when act...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Nishimori, Shigeki, O’Meara, Maureen J., Castro, Christian D., Noda, Hiroshi, Cetinbas, Murat, da Silva Martins, Janaina, Ayturk, Ugur, Brooks, Daniel J., Bruce, Michael, Nagata, Mizuki, Ono, Wanida, Janton, Christopher J., Bouxsein, Mary L., Foretz, Marc, Berdeaux, Rebecca, Sadreyev, Ruslan I., Gardella, Thomas J., Jüppner, Harald, Kronenberg, Henry M., Wein, Marc N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6877304/
https://ncbi.nlm.nih.gov/pubmed/31430259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI130126
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