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Bioinformatics Strategies, Challenges, and Opportunities for Next Generation Sequencing-Based HLA Genotyping

The advent of next generation sequencing (NGS) has altered the face of genotyping the human leukocyte antigen (HLA) system in clinical, stem cell donor registry, and research contexts. NGS has led to a dramatically increased sequencing throughput at high accuracy, while being more time and cost effi...

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Detalhes bibliográficos
Publicado no:Transfus Med Hemother
Main Authors: Klasberg, Steffen, Surendranath, Vineeth, Lange, Vinzenz, Schöfl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876610/
https://ncbi.nlm.nih.gov/pubmed/31832057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000502487
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