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HLA genotyping by next-generation sequencing of complementary DNA

BACKGROUND: Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region. Next-generation sequencing is changing the landscape of genotyping. In...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Genomics
Prif Awduron: Segawa, Hidenobu, Kukita, Yoji, Kato, Kikuya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704545/
https://ncbi.nlm.nih.gov/pubmed/29179676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4300-7
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