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HLA genotyping by next-generation sequencing of complementary DNA

BACKGROUND: Genotyping of the human leucocyte antigen (HLA) is indispensable for various medical treatments. However, unambiguous genotyping is technically challenging due to high polymorphism of the corresponding genomic region. Next-generation sequencing is changing the landscape of genotyping. In...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Segawa, Hidenobu, Kukita, Yoji, Kato, Kikuya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5704545/
https://ncbi.nlm.nih.gov/pubmed/29179676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4300-7
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