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Bioinformatics Strategies, Challenges, and Opportunities for Next Generation Sequencing-Based HLA Genotyping

The advent of next generation sequencing (NGS) has altered the face of genotyping the human leukocyte antigen (HLA) system in clinical, stem cell donor registry, and research contexts. NGS has led to a dramatically increased sequencing throughput at high accuracy, while being more time and cost effi...

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Dettagli Bibliografici
Pubblicato in:Transfus Med Hemother
Autori principali: Klasberg, Steffen, Surendranath, Vineeth, Lange, Vinzenz, Schöfl, Gerhard
Natura: Artigo
Lingua:Inglês
Pubblicazione: S. Karger AG 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876610/
https://ncbi.nlm.nih.gov/pubmed/31832057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000502487
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