Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

Tumor-associated myeloid cells (TAMCs) are key drivers of immunosuppression in the tumor microenvironment, which profoundly impedes the clinical response to immune-dependent and conventional therapeutic modalities. As a hallmark of glioblastoma (GBM), TAMCs are massively recruited to reach up to 50%...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhang, Peng, Miska, Jason, Lee-Chang, Catalina, Rashidi, Aida, Panek, Wojciech K., An, Shejuan, Zannikou, Markella, Lopez-Rosas, Aurora, Han, Yu, Xiao, Ting, Pituch, Katarzyna C., Kanojia, Deepak, Balyasnikova, Irina V., Lesniak, Maciej S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6876152/
https://ncbi.nlm.nih.gov/pubmed/31712430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1906346116
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