A harmonized longitudinal biomarkers and cognition database for assessing the natural history of preclinical Alzheimer disease from young adulthood and for designing prevention trials

INTRODUCTION: Large longitudinal biomarkers database focusing on middle age is needed for AD prevention. METHODS: Data for cerebrospinal fluid (CSF) analytes, molecular imaging of cerebral fibrillar β-amyloid with positron emission tomography (PET), magnetic resonance imaging (MRI)-based brain struc...

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Veröffentlicht in:Alzheimers Dement
Hauptverfasser: Xiong, Chengjie, Luo, Jingqin, Agboola, Folasade, Li, Yan, Albert, Marilyn, Johnson, Sterling C., Koscik, Rebecca L., Masters, Colin L., Soldan, Anja, Villemagne, Victor L., Li, Qiao-Xin, McDade, Eric M., Fagan, Anne M., Massoumzadeh, Parinaz, Benzinger, Tammie, Hassenstab, Jason, Bateman, Randall J., Morris, John C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874758/
https://ncbi.nlm.nih.gov/pubmed/31506247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2019.06.4955
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