Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study

OBJECTIVE: To determine the ordering of changes in Alzheimer disease (AD) biomarkers among cognitively normal individuals. METHODS: Cross-sectional data, including CSF analytes, molecular imaging of cerebral fibrillar β-amyloid (Aβ) with PET using the [(11)C] benzothiazole tracer Pittsburgh compound...

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Published in:Neurology
Main Authors: Luo, Jingqin, Agboola, Folasade, Grant, Elizabeth, Masters, Colin L., Albert, Marilyn S., Johnson, Sterling C., McDade, Eric M., Vöglein, Jonathan, Fagan, Anne M., Benzinger, Tammie, Massoumzadeh, Parinaz, Hassenstab, Jason, Bateman, Randall J., Morris, John C., Perrin, Richard J., Chhatwal, Jasmeer, Jucker, Mathias, Ghetti, Bernardino, Cruchaga, Carlos, Graff-Radford, Neill R., Schofield, Peter R., Mori, Hiroshi, Xiong, Chengjie
Format: Artigo
Language:Inglês
Published: Lippincott Williams & Wilkins 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7734923/
https://ncbi.nlm.nih.gov/pubmed/32873693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000010747
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