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New Alzheimer’s disease model mouse specialized for analyzing the function and toxicity of intraneuronal Amyloid β oligomers

Oligomers of intracellular amyloid β protein (Aβ) are strongly cytotoxic and play crucial roles in synaptic transmission and cognitive function in Alzheimer’s disease (AD). However, there is currently no AD model mouse in which to specifically analyze the function of Aβ oligomers only. We have now d...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Ochiishi, Tomoyo, Kaku, Masami, Kiyosue, Kazuyuki, Doi, Motomichi, Urabe, Takao, Hattori, Nobutaka, Shimura, Hideki, Ebihara, Tatsuhiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6874556/
https://ncbi.nlm.nih.gov/pubmed/31757975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-53415-8
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