Comparative analysis of the catalytic regulation of NEDD4-1 and WWP2 ubiquitin ligases

NEDD4-1 E3 ubiquitin protein ligase (NEDD4-1) and WW domain-containing E3 ubiquitin ligase (WWP2) are HECT family ubiquitin E3 ligases. They catalyze Lys ubiquitination of themselves and other proteins and are important in cell growth and differentiation. Regulation of NEDD4-1 and WWP2 catalytic act...

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Udgivet i:J Biol Chem
Main Authors: Jiang, Hanjie, Thomas, Stefani N., Chen, Zan, Chiang, Claire Y., Cole, Philip A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2019
Fag:
Enzymology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6873185/
https://ncbi.nlm.nih.gov/pubmed/31578285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009211
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