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Genome aging: somatic mutation in the brain links age-related decline with disease and nominates pathogenic mechanisms

Aging is a mysterious process, not only controlled genetically but also subject to random damage that can accumulate over time. While DNA damage and subsequent mutation in somatic cells were first proposed as drivers of aging more than 60 years ago, whether and to what degree these processes shape t...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Hum Mol Genet
Κύριοι συγγραφείς: Lodato, Michael A, Walsh, Christopher A
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6872434/
https://ncbi.nlm.nih.gov/pubmed/31578549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddz191
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