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The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80

Phosphorylation of the NF-κB transcription factor is an important regulatory mechanism for the control of transcription. Here we identify serine 80 (S80) as a phosphorylation site on the p50 subunit of NF-κB, and IKKβ as a p50 kinase. Transcriptomic analysis of cells expressing a p50 S80A mutant rev...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Nucleic Acids Res
मुख्य लेखकों: Smith, Emma L, Somma, Domenico, Kerrigan, David, McIntyre, Zoe, Cole, John J, Liang, Kai Ling, Kiely, Patrick A, Keeshan, Karen, Carmody, Ruaidhrí J
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6868378/
https://ncbi.nlm.nih.gov/pubmed/31598684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz873
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