Mapping the Interaction of B Cell Leukemia 3 (BCL-3) and Nuclear Factor κB (NF-κB) p50 Identifies a BCL-3-mimetic Anti-inflammatory Peptide

The NF-κB transcriptional response is tightly regulated by a number of processes including the phosphorylation, ubiquitination, and subsequent proteasomal degradation of NF-κB subunits. The IκB family protein BCL-3 stabilizes a NF-κB p50 homodimer·DNA complex through inhibition of p50 ubiquitination...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Collins, Patricia E., Grassia, Gianluca, Colleran, Amy, Kiely, Patrick A., Ialenti, Armando, Maffia, Pasquale, Carmody, Ruaidhrí J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505479/
https://ncbi.nlm.nih.gov/pubmed/25922067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.643700
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