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Deubiquitination of NF-κB by Ubiquitin-Specific Protease-7 promotes transcription

NF-κB is the master regulator of the immune response and is responsible for the transcription of hundreds of genes controlling inflammation and immunity. Activation of NF-κB occurs in the cytoplasm through the kinase activity of the IκB kinase complex, which leads to translocation of NF-κB to the nu...

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Detalhes bibliográficos
Main Authors: Colleran, Amy, Collins, Patricia E., O’Carroll, Christine, Ahmed, Abrar, Mao, Xicheng, McManus, Bettina, Kiely, Patrick A., Burstein, Ezra, Carmody, Ruaidhrí J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3545798/
https://ncbi.nlm.nih.gov/pubmed/23267096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1208446110
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