The IκB-protein BCL-3 controls Toll-like receptor-induced MAPK activity by promoting TPL-2 degradation in the nucleus

by Collins, Patricia E., Somma, Domenico, Kerrigan, David, Herrington, Felicity, Keeshan, Karen, Nibbs, Robert J. B., Carmody, Ruaidhrí J.
Published in Proc Natl Acad Sci U S A (2019)

CIKS/DDX3X interaction controls the stability of the Zc3h12a mRNA induced by IL-17

by Somma, Domenico, Mastrovito, Paola, Grieco, Marianeve, Lavorgna, Alfonso, Pignalosa, Angelica, Formisano, Luigi, Salzano, Anna Maria, Scaloni, Andrea, Pacifico, Francesco, Siebenlist, Ulrich, Leonardi, Antonio
Published in J Immunol (2015)

The regulation of sequence specific NF-κB DNA binding and transcription by IKKβ phosphorylation of NF-κB p50 at serine 80

by Smith, Emma L, Somma, Domenico, Kerrigan, David, McIntyre, Zoe, Cole, John J, Liang, Kai Ling, Kiely, Patrick A, Keeshan, Karen, Carmody, Ruaidhrí J
Published in Nucleic Acids Res (2019)

The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits

by Mitxitorena, Izaskun, Somma, Domenico, Mitchell, Jennifer P., Lepistö, Matti, Tyrchan, Christian, Smith, Emma L., Kiely, Patrick A., Walden, Helen, Keeshan, Karen, Carmody, Ruaidhrí J.
Published in J Biol Chem (2020)

Sphingosine Kinases promote IL-17 expression in human T lymphocytes

by Barra, Giusi, Lepore, Alessio, Gagliardi, Miriam, Somma, Domenico, Matarazzo, Maria Rosaria, Costabile, Francesca, Pasquale, Giuseppe, Mazzoni, Alessio, Gallo, Carmela, Nuzzo, Genoveffa, Annunziato, Francesco, Fontana, Angelo, Leonardi, Antonio, De Palma, Raffaele
Published in Sci Rep (2018)

COVID-19 and RA share an SPP1 myeloid pathway that drives PD-L1(+) neutrophils and CD14(+) monocytes

by MacDonald, Lucy, Alivernini, Stefano, Tolusso, Barbara, Elmesmari, Aziza, Somma, Domenico, Perniola, Simone, Paglionico, Annamaria, Petricca, Luca, Bosello, Silvia L., Carfì, Angelo, Sali, Michela, Stigliano, Egidio, Cingolani, Antonella, Murri, Rita, Arena, Vincenzo, Fantoni, Massimo, Antonelli, Massimo, Landi, Francesco, Franceschi, Francesco, Sanguinetti, Maurizio, McInnes, Iain B., McSharry, Charles, Gasbarrini, Antonio, Otto, Thomas D., Kurowska-Stolarska, Mariola, Gremese, Elisa
Published in JCI Insight (2021)