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Atomistic insight into the kinetic pathways for Watson–Crick to Hoogsteen transitions in DNA
DNA predominantly contains Watson–Crick (WC) base pairs, but a non-negligible fraction of base pairs are in the Hoogsteen (HG) hydrogen bonding motif at any time. In HG, the purine is rotated ∼180° relative to the WC motif. The transitions between WC and HG may play a role in recognition and replica...
Enregistré dans:
| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6868366/ https://ncbi.nlm.nih.gov/pubmed/31665440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz837 |
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