Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK

Impaired mitochondrial respiratory activity contributes to the development of insulin resistance in type 2 diabetes. Metformin, a first-line antidiabetic drug, functions mainly by improving patients’ hyperglycemia and insulin resistance. However, its mechanism of action is still not well understood....

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Wang, Yu, An, Hongying, Liu, Ting, Qin, Caolitao, Sesaki, Hiromi, Guo, Shaodong, Radovick, Sally, Hussain, Mehboob, Maheshwari, Akhil, Wondisford, Fredric E., O’Rourke, Brian, He, Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6866677/
https://ncbi.nlm.nih.gov/pubmed/31693892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.09.070
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