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Metformin Improves Mitochondrial Respiratory Activity through Activation of AMPK
Impaired mitochondrial respiratory activity contributes to the development of insulin resistance in type 2 diabetes. Metformin, a first-line antidiabetic drug, functions mainly by improving patients’ hyperglycemia and insulin resistance. However, its mechanism of action is still not well understood....
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| Опубликовано в: : | Cell Rep |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6866677/ https://ncbi.nlm.nih.gov/pubmed/31693892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2019.09.070 |
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