Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)

Metformin is a first-line antidiabetic agent taken by 150 million people across the world every year, yet its mechanism remains only partially understood and controversial. It was proposed that suppression of glucose production in hepatocytes by metformin is AMPK-independent; however, unachievably h...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Cao, Jia, Meng, Shumei, Chang, Evan, Beckwith-Fickas, Katherine, Xiong, Lishou, Cole, Robert N., Radovick, Sally, Wondisford, Fredric E., He, Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2014
Schlagworte:
Gene Regulation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110255/
https://ncbi.nlm.nih.gov/pubmed/24928508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567271
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge