Low Concentrations of Metformin Suppress Glucose Production in Hepatocytes through AMP-activated Protein Kinase (AMPK)

Metformin is a first-line antidiabetic agent taken by 150 million people across the world every year, yet its mechanism remains only partially understood and controversial. It was proposed that suppression of glucose production in hepatocytes by metformin is AMPK-independent; however, unachievably h...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cao, Jia, Meng, Shumei, Chang, Evan, Beckwith-Fickas, Katherine, Xiong, Lishou, Cole, Robert N., Radovick, Sally, Wondisford, Fredric E., He, Ling
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Gene Regulation
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4110255/
https://ncbi.nlm.nih.gov/pubmed/24928508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.567271
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