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Examining the Origin of Catalytic Power of Catechol O-Methyltransferase
For decades, there has been debate regarding the origin of the catalytic power of enzymes. In this work, we use the approach of computational chemistry to study the enzyme catechol O-methyltransferase (COMT) and reveal that the two current views on the catalytic mechanism of enzymes, the rate-promot...
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| Publicado no: | ACS Catal |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6865801/ https://ncbi.nlm.nih.gov/pubmed/31750009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b02657 |
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