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Catechol-O-Methyltransferase Polymorphism and Endometriosis

Purpose: Catechol-O-methyltransferase (COMT) inactivates the estradiol metabolites, 2-hydroxy and 4-hydroxy catechols, which have been implicated in the pathogenesis of endometriosis. A COMT valine to methionine polymorphism (G-to-A) in exon 4 of the COMT gene is polymorphic in the human population,...

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Main Authors: Wieser, Fritz, Wenzl, Rene, Tempfer, Clemens, Worda, Christoph, Huber, Johannes, Schneeberger, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Kluwer Academic Publishers-Plenum Publishers 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3455752/
https://ncbi.nlm.nih.gov/pubmed/12168735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1023/A:1016062726783
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