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Examining the Origin of Catalytic Power of Catechol O-Methyltransferase
For decades, there has been debate regarding the origin of the catalytic power of enzymes. In this work, we use the approach of computational chemistry to study the enzyme catechol O-methyltransferase (COMT) and reveal that the two current views on the catalytic mechanism of enzymes, the rate-promot...
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| Pubblicato in: | ACS Catal |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6865801/ https://ncbi.nlm.nih.gov/pubmed/31750009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.9b02657 |
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