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Synthesis of Novel Triazinoindole-Based Thiourea Hybrid: A Study on α-Glucosidase Inhibitors and Their Molecular Docking
A new class of triazinoindole-bearing thiosemicarbazides (1–25) was synthesized and evaluated for α-glucosidase inhibitory potential. All synthesized analogs exhibited excellent inhibitory potential, with IC(50) values ranging from 1.30 ± 0.01 to 35.80 ± 0.80 μM when compared to standard acarbose (a...
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| 出版年: | Molecules |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6864627/ https://ncbi.nlm.nih.gov/pubmed/31652777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213819 |
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