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Synthesis of new isoquinoline-base-oxadiazole derivatives as potent inhibitors of thymidine phosphorylase and molecular docking study

Here in this study regarding the over expression of TP, which causes some physical, mental and socio problems like psoriasis, chronic inflammatory disease, tumor angiogenesis and rheumatoid arthritis etc. By this consideration, the inhibition of this enzyme is vital to secure life from serious threa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zaman, Khalid, Rahim, Fazal, Taha, Muhammad, Wadood, Abdul, Shah, Syed Adnan Ali, Ahmed, Qamar Uddin, Zakaria, Zainul Amiruddin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831664/
https://ncbi.nlm.nih.gov/pubmed/31690793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52100-0
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