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Synthesis, in vitro urease inhibitory potential and molecular docking study of benzofuran-based-thiazoldinone analogues

In continuation of our work on enzyme inhibition, the benzofuran-based-thiazoldinone analogues (1–14) were synthesized, characterized by HREI-MS, (1)H and (13)CNMR and evaluated for urease inhibition. Compounds 1–14 exhibited a varying degree of urease inhibitory activity with IC(50) values between...

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書目詳細資料
發表在:Sci Rep
Main Authors: Taha, Muhammad, Rahim, Fazal, Ullah, Hayat, Wadood, Abdul, Farooq, Rai Khalid, Shah, Syed Adnan Ali, Nawaz, Muhammad, Zakaria, Zainul Amiruddin
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7326984/
https://ncbi.nlm.nih.gov/pubmed/32606439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-67414-7
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